Drosophila Perlecan Regulates Intestinal Stem Cell Activity via Cell-Matrix Attachment
نویسندگان
چکیده
منابع مشابه
Drosophila Perlecan Regulates Intestinal Stem Cell Activity via Cell-Matrix Attachment
Stem cells require specialized local microenvironments, termed niches, for normal retention, proliferation, and multipotency. Niches are composed of cells together with their associated extracellular matrix (ECM). Currently, the roles of ECM in regulating niche functions are poorly understood. Here, we demonstrate that Perlecan (Pcan), a highly conserved ECM component, controls intestinal stem ...
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ژورنال
عنوان ژورنال: Stem Cell Reports
سال: 2014
ISSN: 2213-6711
DOI: 10.1016/j.stemcr.2014.04.007